Check CLAIMS ANTI-ACNE of your product by following
National and International methodologies

WHAT IS ACNE?


Acne vulgaris is a chronic dermatologic disease relating to blockage and/or inflammation of the pilosebaceous unit. It can be characterized by non-inflammatory (comedone) and inflammatory (papule and pustule) skin spots which mostly appear in the sebum-rich areas such as face, back, and chest. The pathogenesis of acne is probably multifactorial, it being related to an interaction among some factors such as increased sebum production by pilosebaceous glands, keratinocyte hyperproliferation, bacteria colonization (especially Propionibacterium acnes, i.e. P. acnes) in hair follicle, primary perifollicular inflammation, and inflammatory responses to P. acnes metabolites, cell debris and/or sebum.

Therefore, acnegenicity clinical trials for cosmetic products can be carried out for two purposes: to evaluate the effectiveness of test products in the treatment of acne lesions or to evaluate the acnegenic potential of test products. In both scenarios, we can support some interesting claims based on Expert grader assessment and/or instrumental analysis:

WHAT CLAIMS CAN WE SUPPORT?



    Clinical efficacy assessment by a dermatologist - We assess the products based on an assessment scale;

    Supported by dermatological clinical assessment;

    Acne lesions assessment (counts and visibility, blackheads, whiteheads) before and after the use of the product; redness and porforins (produced by bacteria Propionibacterium acnes and measured directly on the captured photographs.) assessment by standardized digital photographs (Visia-CR, colorface)

    Pores analysis – diameter, deepness (visia, colorface, confocal)

    Skin surface sebum level evaluation (sebumeter)

    Exfoliation evaluation (Visioscan)

    pH evaluation during the use of the product (pH Meter)

    Moisturizes the skin (corneometer)

    Barrier function evaluation, skin water loss assessment (TEWL)

    Number and percentage (confocal)